abstract：:The association between the extent of left ventricular (LV) hypertrophy and severity of ventricular or atrial arrhythmias are examined. Two-dimensional echocardiography and 24-h Holter electrocardiography monitoring were performed in 60 patients with hypertrophic cardiomyopathy (HCM). According to the distribution of ...

journal_title：Acta medica Okayama

authors： Cheng XS,Kusachi S,Urabe N,Nogami K,Takemoto M,Morishita N,Haraoka S,Tsuji T

更新日期：1991-06-01 00:00:00

abstract：:DNA repair synthesis induced in permeable mouse ascites sarcoma cells by peplomycin, an antitumor antibiotic, was studied. Mouse ascites sarcoma (SR-C3H/He) cells were permeabilized with a low concentration of Triton X-100 in an isotonic condition. Permeable cells were treated with an appropriate concentration of pepl...

journal_title：Acta medica Okayama

authors： Zhang B,Watanabe S,Akiyama K,Li T,Fukushima K,Tsutsui K,Seki S

更新日期：1991-04-01 00:00:00

abstract：:Eighty-two patients with sporadic acute viral hepatitis were detected at Okayama University Hospital between January 1982 and March 1989. Thirty of them had non-A, non-B hepatitis (NANBH); 20 had hepatitis A (HA); and 32 had hepatitis B (HB). Ten (33%) of NANBH, five (25%) of HA, and nine (28%) cases of HB were hospit...

journal_title：Acta medica Okayama

authors： Takahashi M,Yamada G,Tsuji T

更新日期：1990-12-01 00:00:00

abstract：:We report a case of a non-Hodgkin's lymphoma (NHL) patient treated successfully with combination chemotherapy during pregnancy who delivered a full-term baby. A 29 year-old patient with cervical and inguinal lymphadenopathy in the 27th week of gestation was referred to our hospital. The diagnosis of lymph node biopsy ...

journal_title：Acta medica Okayama

authors： Toki H,Okabe K,Kamei H,Shimokawa T,Hiura M,Kondo M,Hirota Y

更新日期：1990-12-01 00:00:00

abstract：:A rare gastrointestinal tract neoplasm, primary non-Hodgkin's B-cell lymphoma in a 39-year-old, asymptomatic woman is described. The tumor was originally localized in the rectum without evidence of any other lymphoma-involved organ and treated by curative surgical procedure associated with postoperative chemotherapy. ...

journal_title：Acta medica Okayama

authors： Moreira LF,Iwagaki H,Watanabe K,Yoshino T,Fuchimoto S,Orita K

更新日期：1990-10-01 00:00:00

abstract：:We studied the brains of two cases of amyotrophic lateral sclerosis with dementia. Bunina bodies were found in the motor neurons of cranial nerve nuclei (trigeminal, facial and hypoglossal nerves) as well as in the spinal motoneurons. They appeared mostly in the cytoplasm and occasionally in the neuronal processes. Ho...

journal_title：Acta medica Okayama

authors： Kuroda S,Ishizu H,Kawai K,Otsuki S

更新日期：1990-02-01 00:00:00

abstract：:In vivo inactivation of cystathionine gamma-lyase by D,L-propargylglycine, a suicide inhibitor, was found to be less profound in rat kidney than in the liver. We investigated the cause of this difference using rat tissues. We fractionated kidney extract to characterize the substance which protected enzyme, and found t...

journal_title：Acta medica Okayama

authors： Awata S,Nakayama K,Suzuki I,Kodama H

更新日期：1989-12-01 00:00:00

abstract：:Chlorpyrifos, an organophosphorus insecticide, has been used to control termites since regulatory measures against the use of chlordanes were taken in September, 1986. We developed an improved gas chromatographic (GC) method for the assay of 3,5,6-trichloro-2-pyridinol (TCP) in the urine to use in the biological monit...

journal_title：Acta medica Okayama

authors： Jitsunari F,Asakawa F,Nakajima T,Shimada J,Ogata M

更新日期：1989-10-01 00:00:00

abstract：:The plasma fatty acid composition of cirrhotic patients and their dietary intake of fatty acids were determined. Significantly lower plasma arachidonic, docosahexaenoic, dihomo-gamma-linolenic and eicosapentaenoic acid levels were observed in cirrhotic patients than in healthy controls. A remarkably low dietary intake...

journal_title：Acta medica Okayama

authors： Okita M,Watanabe A,Tsuji T

更新日期：1989-02-01 00:00:00

abstract：:Eradication of immunologically-syngeneic tumors was achieved by adoptive chemotherapy using effector cells induced by Corynebacterium parvum-Pyridine Extract Residue (CP-PER). A mixture of 2 X 10(6) Meth A cells and 0.1 mg CP-PER was subcutaneously inoculated into the back of donor BALB/c mice, with the result that th...

journal_title：Acta medica Okayama

authors： Mukai K,Horimi T,Orita K

更新日期：1988-12-01 00:00:00

abstract：:A case of malignant lymphoma associated with complete heart block in a 30-year-old woman is reported. The patient progressively deteriorated despite temporary pacing and died 24 days after being admitted. Microscopic examination of the heart revealed marked infiltration by lymphoma cells in the atrioventricular node a...

journal_title：Acta medica Okayama

authors： Shigenobu M,Mukuzono H,Teramoto S

更新日期：1988-12-01 00:00:00

abstract：:The effects of prolonged weak anodal direct current (DC) on the electrocorticogram (ECoG) were investigated in awake rabbits. When the current (20-40 microA) was applied to the motor region of the cerebral cortex, seizure activity in the ECoG appeared from the frontal cortex. Repeated application of the DC decreased t...

journal_title：Acta medica Okayama

authors： Hayashi Y,Hattori Y,Moriwaki A,Asaki H,Hori Y

更新日期：1988-10-01 00:00:00

abstract：:To study the polarity of the efferent pathway of the myenteric plexus, recordings were made of the mechanical activity of the longitudinal muscle of isolated guinea-pig ileal segments upon stimulation with an electrical field around the myenteric plexus contained within strips of longitudinal muscle (LM-MP) continuous...

journal_title：Acta medica Okayama

authors： Jin JG,Neya T,Takaki M

更新日期：1988-06-01 00:00:00

abstract：:The cartilage-synovium junction of knees afflicted with rheumatoid arthritis was observed light microscopically using formalin-fixed, decalcified and immunohistochemically stained tissues. Decalcification had little or no influence on immunoreactivity for lysozyme and S-100 protein. All the specimens had pannus format...

journal_title：Acta medica Okayama

authors： Takasugi S,Inoue H

更新日期：1988-04-01 00:00:00

abstract：:The role of the lumbar sympathetic nerves and supraspinal mechanism in the defecation reflex was investigated in 30 adult cats and 6 kittens. One or two propulsive contractions, whose mean pressure evoked was more than about 90 cmH2O (adult cats) and 50 cmH2O (kittens), were induced in the rectum of all animals by rec...

journal_title：Acta medica Okayama

authors： Takaki M,Neya T,Nakayama S

更新日期：1987-12-01 00:00:00

abstract：:The anti-ulcer action of clotiazepam (a thienodiazepine derivative) was studied in mice subjected to non-physical and physical stimuli in a communication box. There were two groups of mice: the "sender" mice that received electric shocks on the feet and responded by squealing and jumping, and the "responder" mice that...

journal_title：Acta medica Okayama

authors： Gomita Y,Ichimaru Y,Ohizumi N,Yamada H,Moriyama M,Araki Y

更新日期：1987-12-01 00:00:00

abstract：:The thalamic posterior ventral neurons with bifurcating axons to both the first and second somatosensory cortical areas (SI and SII) in the cat were examined by the fluorescent retrograde double labeling technique. After injection of Evans blue (EB) into the SI, and of 4',6-diamidino-2-phenylindol.2HCl (DAPI) into the...

journal_title：Acta medica Okayama

authors： Yanagihara M,Niimi K,Imataki T

更新日期：1987-12-01 00:00:00

abstract：:The cytostatic and cytotoxic effects of highly purified natural human tumor necrosis factor (HuTNF-alpha) and natural human interferon-alpha (HuIFN-alpha) on 23 cell lines were studied in vitro. Natural HuTNF-alpha showed cytostatic and cytotoxic effects on PC-9, KHG-2, HT-1197, KG-1 and L-929 cells, and HuIFN-alpha s...

journal_title：Acta medica Okayama

authors： Orita K,Ando S,Kurimoto M

更新日期：1987-08-01 00:00:00

abstract：:The extra-anatomical bypass formation and the exclusion of thoracic aortic aneurysms by the "paired clamp method" applied to the thoracic aorta of mongrel dogs, and the development of hind leg paralysis was studied experimentally in relation to the ratio between the mean excluded cavity pressure and the mean aortic pr...

journal_title：Acta medica Okayama

authors： Imawaki S

更新日期：1987-06-01 00:00:00

abstract：:Protective effects of clinically used drugs against adriamycin (ADM)-induced toxicity were studied in ICR mice. The control mice, which were administered 15 mg/kg of ADM twice, survived 7.48 +/- 1.99 days (mean +/- S.D.). The survival times of mice treated with the following drugs, expressed as a percent of that of th...

journal_title：Acta medica Okayama

authors： Shinozawa S,Gomita Y,Araki Y

更新日期：1987-02-01 00:00:00

abstract：:Accumulation of cyclic AMP elicited by glutamate was examined in slices from different cortical areas of rats 30 to 60 days after ferrous chloride solution was injected into the left sensorimotor cortex to induce an epileptic focus. In the anterior cortex of rats showing dominant electrographic spike activity on eithe...

journal_title：Acta medica Okayama

authors： Hattori Y,Moriwaki A,Hayashi Y,Hori Y

更新日期：1986-10-01 00:00:00

abstract：:In an attempt to evaluate high density lipoprotein (HDL) subfraction levels in liver diseases, HDL was separated by a precipitation method with dextran sulfate-Mg2+ from sera of 289 healthy adults and 50 patients with liver diseases. The HDL was subdivided into HDL2e and HDL3e by Utermann's polyacrylamide gel electrop...

journal_title：Acta medica Okayama

authors： Ikeda S

更新日期：1986-06-01 00:00:00

abstract：:Twenty-five patients with intractable asthma had swimming training in a hot spring pool for 3 months. The subjects were divided into three groups according to their clinical symptoms and ages. Changes of ventilatory function during swimming training were observed in in each group. The ventilatory function test reveale...

journal_title：Acta medica Okayama

authors： Tanizaki Y

更新日期：1986-02-01 00:00:00

abstract：:Age-related alterations in the host defense system have been vigorously investigated because of increased susceptibility to infection and neoplasms in the aged. Although monocyte-macrophages form a major part of the cellular defense against microorganisms, the majority of investigations has been limited to neutrophils...

journal_title：Acta medica Okayama

authors： Takahashi I,Ohmoto E,Aoyama S,Takizawa M,Oda Y,Nonaka K,Nakada H,Yorimitsu S,Kimura I

更新日期：1985-12-01 00:00:00

abstract：:Vecuronium is hydrolyzed in the body to 3-deacetyl (ORG 7268), 17-deacetyl (ORG NC58), and 3, 17-bis-deacetyl (ORG 7402) derivatives. Interactions of vecuronium and these metabolites were studied in phrenic nerve-hemidiaphragm preparations of rats. As already reported, ORG 7268 had a potent neuromuscular blocking acti...

journal_title：Acta medica Okayama

authors： Ohta Y

更新日期：1985-12-01 00:00:00

abstract：:Twenty-five patients (30 hips) have had a total hip replacement using the cup supporter developed in our department. This report describes the follow-up findings on these patients. The mean period after hip replacement was 2 years and 8 months (range from 6 months to 6 years). The cup supporter was used in patients wi...

journal_title：Acta medica Okayama

authors： Takahashi T

更新日期：1985-10-01 00:00:00

abstract：:Polyamines are polycationic substances which are widely distributed in living organisms and have a close relation to rapid growth phenomena. We examined ornithine decarboxylase (ODC), which is the rate limiting enzyme of polyamine biosynthesis, and polyamine induction in primary cultured rat hepatocytes by various hor...

journal_title：Acta medica Okayama

authors： Hiramatsu Y,Eguchi K,Sekiba K

更新日期：1985-08-01 00:00:00

abstract：:We report a family whose members have familial spastic paraplegia (FSP) associated with epilepsy. A man and his sister initially had primary generalized epilepsy with tonic-clonic seizures, but they have had no seizures for years. However, they developed spastic paresis of the lower extremities and presently show feat...

journal_title：Acta medica Okayama

authors： Kuroda S,Kazahaya Y,Otsuki S,Takahashi S

更新日期：1985-04-01 00:00:00

abstract：:We made a scanning electron-microscopic study of the angioarchitecture of the rabbit iris using vascular resin casts, and compared the vascular structure in miosis to that in mydriasis. There were three vascular layers in the iris: the anterior capillary layer, arteriolo-venular layer and posterior capillary layer. Th...

journal_title：Acta medica Okayama

authors： Ojima M,Matsuo N

更新日期：1985-02-01 00:00:00

abstract：:Ferrous chloride solution was injected unilaterally into the sensorimotor cortex of rats to induce a chronic epileptic focus. Accumulation of cyclic AMP elicited by depolarizing agents was determined in slices from different cortical areas of rats 30-60 days after the injection. In anterior cortical areas which includ...

journal_title：Acta medica Okayama

authors： Hattori Y,Moriwaki A,Yasuhara H,Nishida N,Hori Y

更新日期：1984-10-01 00:00:00

abstract：:The concentrations and alpha-methyl-p-tyrosine (alpha-MPT) induced disappearance of catecholamines, adrenaline, noradrenaline and dopamine, were measured in selected areas of the brainstem and hypothalamus of spontaneously hypertensive rats (SHR) and deoxycorticosterone acetate (DOCA)-salt hypertensive rats. The catec...

journal_title：Acta medica Okayama

authors： Fujino K

更新日期：1984-08-01 00:00:00

abstract：:Plasma immunoreactive CRF measured by radioimmunoassay decreased rapidly after intravenous injection of synthetic ovine corticotropin releasing factor (CRF) and showed a bi-exponential decay curve in five macaca fuscatas. Half lives of plasma immunoreactive CRF were 5.8 +/- 1.4 (Mean +/- SEM) min for the fast componen...

journal_title：Acta medica Okayama

authors： Hashimoto K,Murakami K,Hattori T,Ota Z

更新日期：1984-06-01 00:00:00

abstract：:Spleen cells serially sampled from normal mice following partial hepatectomy were tested for antibody-dependent cellular cytotoxicity (ADCC) and natural killer (NK) activity. There was a marked augmentation of these activities of spleen cells from the hepatectomized animals, compared to cells from controls with a simp...

journal_title：Acta medica Okayama

authors： Ono M,Tanaka N,Orita K

更新日期：1984-04-01 00:00:00

abstract：:The basilar artery was exposed transclivally , and a vascular spasm was produced by topical application of a lysed erythrocyte solution. The maximum fall in the mean arterial blood pressure (MABP) after administering of 2 micrograms/ kgBW and 15 micrograms/ kgBW of PGI2, ranged from 35 to 45 mmHg and from 65 to 85 mmH...

journal_title：Acta medica Okayama

authors： Yabuno N

更新日期：1984-04-01 00:00:00

abstract：:The whole body including extended processes of Ito's fat-storing cells was observed by scanning electron microscopy in rat liver injured with lithocholic acid (LCA). Necrotic foci developed in the midlobular zone 48 h after LCA administration. Demonstration of Ito cell bodies around the foci was probably facilitated b...

journal_title：Acta medica Okayama

authors： Ito T,Itoshima T,Ukida M,Tobe K,Kiyotoshi S,Kawaguchi K,Ogawa H,Yamamoto H,Hattori S,Kitadai M

更新日期：1984-02-01 00:00:00

abstract：:Levamisole (LMS) was given to stage III gastric cancer patients starting three days before gastrectomy, at a does of 150 mg/day for three consecutive days every other week. Survival rates of these patients were compared with those of stage III gastric cancer patients previously operated in our Department who had not r...

journal_title：Acta medica Okayama

authors： Miwa H,Orita K

更新日期：1983-12-01 00:00:00

abstract：:Active enhancement was induced in inbred rats with cardiac allografts using semisoluble antigens. The optimal time of antigen pretreatment and optimal dose of semisoluble antigens were examined. The presence of serum blocking factors in the sera of rats having had allografts for a long time was examined with a macroph...

journal_title：Acta medica Okayama

authors： Fuchimoto S

更新日期：1983-12-01 00:00:00

abstract：:Computed tomographic arteriography (CTA) was performed in 30 patients with hepatocellular carcinoma (HCC). Detection of HCC by CTA was compared with that of conventional celiac or hepatic arteriography. CT scanning was performed immediately, 30 seconds and 1 min after an injection of 5 to 10 ml of contrast medium into...

journal_title：Acta medica Okayama

authors： Ito T,Yamamoto H,Itoshima T,Ukida M,Ogawa H,Kitadai M,Hattori S,Mizutani S,Kita K,Tanaka R

更新日期：1983-12-01 00:00:00

abstract：:The blood levels of amino acids, ammonia and pancreatic hormones following the intragastric and intravenous administration of a branched-chain amino acid (BCAA)-enriched solution were comparatively investigated in control subjects and patients with liver cirrhosis. There was no essential difference in the time course ...

journal_title：Acta medica Okayama

authors： Watanabe A,Hayashi S,Shiota T,Nagashima H

更新日期：1983-10-01 00:00:00

abstract：:In order to increase the accuracy of diagnosis in lung cancer, analysis concerning cytological and histological correlation was attempted. The present study consists of 106 patients, who were seen during the past approximately five years and underwent radical surgery to remove tumors completely; mere biopsy specimens ...

journal_title：Acta medica Okayama

authors： Tanaka T,Yamamoto M,Tamura T,Moritani Y,Miyai M,Hiraki S,Ohnoshi T,Kimura I

更新日期：1983-02-01 00:00:00